PhytophthoraV1, Main, Exploration, bibRecord, 000233

Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.

Identifieur interne : 000233 ( Main/Exploration ); précédent : 000232; suivant : 000234

Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.

Source :

Journal of integrative plant biology [ 1744-7909 ] ; 2020.

RBID : pubmed:31691466

Descripteurs français

KwdFr :
- Clustered regularly interspaced short palindromic repeats (génétique), Génotype (MeSH), Maladies des plantes (génétique), Maladies des plantes (microbiologie), Phytophthora (pathogénicité), Polymorphisme génétique (génétique), Régions promotrices (génétique) (génétique).
MESH :
- génétique : Clustered regularly interspaced short palindromic repeats, Maladies des plantes, Polymorphisme génétique, Régions promotrices (génétique).
- microbiologie : Maladies des plantes.
- pathogénicité : Phytophthora.
- Génotype.

English descriptors

KwdEn :
- Clustered Regularly Interspaced Short Palindromic Repeats (genetics), Genotype (MeSH), Phytophthora (pathogenicity), Plant Diseases (genetics), Plant Diseases (microbiology), Polymorphism, Genetic (genetics), Promoter Regions, Genetic (genetics).
MESH :
- genetics : Clustered Regularly Interspaced Short Palindromic Repeats, Plant Diseases, Polymorphism, Genetic, Promoter Regions, Genetic.
- microbiology : Plant Diseases.
- pathogenicity : Phytophthora.
- Genotype.

Abstract

Pathogen avirulence (Avr) effectors interplay with corresponding plant resistance (R) proteins and activate robust plant immune responses. Although the expression pattern of Avr genes has been tied to their functions for a long time, it is still not clear how Avr gene expression patterns impact plant-microbe interactions. Here, we selected PsAvr3b, which shows a typical effector gene expression pattern from a soybean root pathogen Phytophthora sojae. To modulate gene expression, we engineered PsAvr3b promoter sequences by in situ substitution with promoter sequences from Actin (constitutive expression), PsXEG1 (early expression), and PsNLP1 (later expression) using the CRISPR/Cas9. PsAvr3b driven by different promoters resulted in distinct expression levels across all the tested infection time points. Importantly, those mutants with low PsAvr3b expression successfully colonized soybean plants carrying the cognate R gene Rps3b. To dissect the difference in plant responses to the PsAvr3b expression level, we conducted RNA-sequencing of different infection samples at 24 h postinfection and found soybean immune genes, including a few previously unknown genes that are associated with resistance. Our study highlights that fine-tuning in Avr gene expression impacts the compatibility of plant disease and provides clues to improve crop resistance in disease control management.

DOI: 10.1111/jipb.12883
PubMed: 31691466

Affiliations:

République populaire de Chine, États-Unis

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<term>Genotype (MeSH)</term>
<term>Phytophthora (pathogenicity)</term>
<term>Plant Diseases (genetics)</term>
<term>Plant Diseases (microbiology)</term>
<term>Polymorphism, Genetic (genetics)</term>
<term>Promoter Regions, Genetic (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Clustered regularly interspaced short palindromic repeats (génétique)</term>
<term>Génotype (MeSH)</term>
<term>Maladies des plantes (génétique)</term>
<term>Maladies des plantes (microbiologie)</term>
<term>Phytophthora (pathogénicité)</term>
<term>Polymorphisme génétique (génétique)</term>
<term>Régions promotrices (génétique) (génétique)</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Clustered Regularly Interspaced Short Palindromic Repeats</term>
<term>Plant Diseases</term>
<term>Polymorphism, Genetic</term>
<term>Promoter Regions, Genetic</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Clustered regularly interspaced short palindromic repeats</term>
<term>Maladies des plantes</term>
<term>Polymorphisme génétique</term>
<term>Régions promotrices (génétique)</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Maladies des plantes</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Plant Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Phytophthora</term>
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<front><div type="abstract" xml:lang="en">Pathogen avirulence (Avr) effectors interplay with corresponding plant resistance (R) proteins and activate robust plant immune responses. Although the expression pattern of Avr genes has been tied to their functions for a long time, it is still not clear how Avr gene expression patterns impact plant-microbe interactions. Here, we selected PsAvr3b, which shows a typical effector gene expression pattern from a soybean root pathogen Phytophthora sojae. To modulate gene expression, we engineered PsAvr3b promoter sequences by in situ substitution with promoter sequences from Actin (constitutive expression), PsXEG1 (early expression), and PsNLP1 (later expression) using the CRISPR/Cas9. PsAvr3b driven by different promoters resulted in distinct expression levels across all the tested infection time points. Importantly, those mutants with low PsAvr3b expression successfully colonized soybean plants carrying the cognate R gene Rps3b. To dissect the difference in plant responses to the PsAvr3b expression level, we conducted RNA-sequencing of different infection samples at 24 h postinfection and found soybean immune genes, including a few previously unknown genes that are associated with resistance. Our study highlights that fine-tuning in Avr gene expression impacts the compatibility of plant disease and provides clues to improve crop resistance in disease control management.</div>
</front>
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<DateCompleted><Year>2020</Year>
<Month>11</Month>
<Day>09</Day>
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<Month>Mar</Month>
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<Title>Journal of integrative plant biology</Title>
<ISOAbbreviation>J Integr Plant Biol</ISOAbbreviation>
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<ArticleTitle>Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.</ArticleTitle>
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<Abstract><AbstractText>Pathogen avirulence (Avr) effectors interplay with corresponding plant resistance (R) proteins and activate robust plant immune responses. Although the expression pattern of Avr genes has been tied to their functions for a long time, it is still not clear how Avr gene expression patterns impact plant-microbe interactions. Here, we selected PsAvr3b, which shows a typical effector gene expression pattern from a soybean root pathogen Phytophthora sojae. To modulate gene expression, we engineered PsAvr3b promoter sequences by in situ substitution with promoter sequences from Actin (constitutive expression), PsXEG1 (early expression), and PsNLP1 (later expression) using the CRISPR/Cas9. PsAvr3b driven by different promoters resulted in distinct expression levels across all the tested infection time points. Importantly, those mutants with low PsAvr3b expression successfully colonized soybean plants carrying the cognate R gene Rps3b. To dissect the difference in plant responses to the PsAvr3b expression level, we conducted RNA-sequencing of different infection samples at 24 h postinfection and found soybean immune genes, including a few previously unknown genes that are associated with resistance. Our study highlights that fine-tuning in Avr gene expression impacts the compatibility of plant disease and provides clues to improve crop resistance in disease control management.</AbstractText>
<CopyrightInformation>© 2019 Institute of Botany, Chinese Academy of Sciences.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ochola</LastName>
<ForeName>Sylvans</ForeName>
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<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Jie</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, 210095, China.</Affiliation>
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<ForeName>Haidong</ForeName>
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<Author ValidYN="Y"><LastName>Shen</LastName>
<ForeName>Danyu</ForeName>
<Initials>D</Initials>
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<Initials>M</Initials>
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</AffiliationInfo>
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<ForeName>Liyuan</ForeName>
<Initials>L</Initials>
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</AffiliationInfo>
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<ForeName>Xi</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.</Affiliation>
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<ForeName>Han</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.</Affiliation>
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<ForeName>Alex</ForeName>
<Initials>A</Initials>
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</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Qutob</LastName>
<ForeName>Dinah</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Math and Science, Walsh University, North Canton, OH, 44720, USA.</Affiliation>
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<ForeName>Suomeng</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, 210095, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, 210095, China.</Affiliation>
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<Agency>National Natural Science Foundation of China</Agency>
<Country></Country>
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<Agency>National Natural Science Foundation of China</Agency>
<Country></Country>
</Grant>
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<Month>12</Month>
<Day>19</Day>
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<MedlineTA>J Integr Plant Biol</MedlineTA>
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<ISSNLinking>1672-9072</ISSNLinking>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D064112" MajorTopicYN="N">Clustered Regularly Interspaced Short Palindromic Repeats</DescriptorName>
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</MeshHeading>
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</MeshHeading>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011401" MajorTopicYN="N">Promoter Regions, Genetic</DescriptorName>
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<Month>08</Month>
<Day>09</Day>
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<Month>10</Month>
<Day>31</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>11</Month>
<Day>7</Day>
<Hour>6</Hour>
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<Hour>6</Hour>
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<affiliations><list><country><li>République populaire de Chine</li>
<li>États-Unis</li>
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   |wiki=    Bois
   |area=    PhytophthoraV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:31691466
   |texte=   Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.
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	Serveur d'exploration Phytophthora
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Serveur d'exploration Phytophthora

Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.

Editing of an effector gene promoter sequence impacts plant-Phytophthora interaction.

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